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BBT

Axon 4313
CAS:  445000-45-3
Purity:  99%
  • Soluble in DMSO and EtOH
  • MF:  C18H12BrNO2S
  • MW:  386.26

Description

BBT potentiates glucose-stimulated insulin secretion (GSIS), protects β-cells, and effectively improves glucose homeostasis in type 2 diabetic mice. The cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathways were involved in the action of BBT against GSIS, and that the cAMP/PKA pathway was essential for the protective action of BBT on β-cells.

More Information

Parent CAS No. 445000-45-3
Chemical Name N-2-Benzoylphenyl-5-bromo-2-thenamide
SMILES C1=C(C(=O)C2=C(NC(=O)C3SC(Br)=CC=3)C=CC=C2)C=CC=C1
MFCD N.A.
InChi InChI=1S/C18H12BrNO2S/c19-16-11-10-15(23-16)18(22)20-14-9-5-4-8-13(14)17(21)12-6-2-1-3-7-12/h1-11H,(H,20,22)
InChiKey FCSCANHTNNHZOH-UHFFFAOYSA-N
CID 1008832
Short Description GSIS potentiatior

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