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ZT-1a
Axon 4101
CAS:
212135-62-1
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C22H15Cl3N2O2
- MW: 445.73
Description
ZT-1a is a potent and selective non-ATP-competitive SPAK inhibitor. Moreover, ZT-1a inhibits NKCC1 and stimulates KCCs by decreasing their SPAK-dependent phosphorylation.
More Information
| Parent CAS No. | 212135-62-1 |
|---|---|
| Chemical Name | 5-Chloro-N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxybenzamide |
| SMILES | C1C(O)=C(C(=O)NC2C=C(Cl)C(C(C#N)C3C=CC(Cl)=CC=3)=CC=2C)C=C(Cl)C=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C22H15Cl3N2O2/c1-12-8-16(18(11-26)13-2-4-14(23)5-3-13)19(25)10-20(12)27-22(29)17-9-15(24)6-7-21(17)28/h2-10,18,28H,1H3,(H,27,29) |
| InChiKey | RPTKRVXJNWPJLU-UHFFFAOYSA-N |
| CID | 10789506 |
| Short Description | SPAK inhibitor |
