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AZD7648

Axon 4068
CAS:  2230820-11-6
Purity:  99%
  • Soluble in DMSO
  • MF:  C18H20N8O2
  • MW:  380.4

Description

AZD7648 is an orally available potent and selective next generation DNA-dependent protein kinase (DNA-PK) inhibitor with enzymatic and cellular IC50 values of 0.6 nM and 91 nM, respectively.

More Information

Parent CAS No. 2230820-11-6
Chemical Name 7-Methyl-2-(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-ylamino)-9-(tetrahydro-2H-pyran-4-yl)-7H-purin-8(9H)-one
SMILES N12N=CN=C1C=C(C)C(NC1N=C3N(C4CCOCC4)C(=O)N(C)C3=CN=1)=C2
MFCD N.A.
InChi InChI=1S/C18H20N8O2/c1-11-7-15-20-10-21-25(15)9-13(11)22-17-19-8-14-16(23-17)26(18(27)24(14)2)12-3-5-28-6-4-12/h7-10,12H,3-6H2,1-2H3,(H,19,22,23)
InChiKey XISVSTPEXYIKJL-UHFFFAOYSA-N
CID 135151360
Short Description DNA-PK inhibitor

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