Bulk Inquiry
LG100268
- LG268
Axon 4017
CAS:
153559-76-3
Purity:
98%
- Soluble in DMSO and EtOH
- MF: C24H29NO2
- MW: 363.49
Description
LG100268 is a potent and selective RXR agonist with EC50 values of 4, 3, and 4 nM for RXRα, RXRβ, and RXRγ, respectively.
More Information
| Parent CAS No. | 153559-76-3 |
|---|---|
| Chemical Name | 6-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl)nicotinic acid |
| SMILES | C1C(C)(C)C2C=C(C3(CC3)C3N=CC(C(O)=O)=CC=3)C(C)=CC=2C(C)(C)C1 |
| MFCD | MFCD01758574 |
| InChi | InChI=1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27) |
| InChiKey | SLXTWXQUEZSSTJ-UHFFFAOYSA-N |
| CID | 3922 |
| Short Description | RXR agonist |
References
- MF Boehm et al. Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem. 1995 Aug 4;38(16):3146-55.
- JD Love et al. The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12. J Biol Chem. 2002 Mar 29;277(13):11385-91.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1700 | Bexarotene |
From $71.50 |
| 2408 | NRX 194204 |
From $132.00 |
| 3003 | HX600 |
From $165.00 |
| 3727 | SR11237 |
From $132.00 |
Other Categories
Get a Quote for
Loading...