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BC-1215
Axon 3898
CAS:
1507370-20-8
Purity:
99%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C26H26N4
- MW: 394.51
Description
BC-1215 is a selective and reversible Fbxo3 inhibitor. BC-1215 reduced TRAF protein levels, which potently inhibited cytokine release from human blood mononuclear cells. BC-1215 effectively lessened the severity of viral pneumonia, septic shock, colitis, and cytokine-driven inflammation systemically in murine models.
More Information
| Parent CAS No. | 1507370-20-8 |
|---|---|
| Chemical Name | N1,N2-Bis(4-(pyridin-2-yl)benzyl)ethane-1,2-diamine |
| SMILES | C1C=C(C2C=CC(CNCCNCC3C=CC(C4C=CC=CN=4)=CC=3)=CC=2)N=CC=1 |
| MFCD | MFCD28118991 |
| InChi | InChI=1S/C26H26N4/c1-3-15-29-25(5-1)23-11-7-21(8-12-23)19-27-17-18-28-20-22-9-13-24(14-10-22)26-6-2-4-16-30-26/h1-16,27-28H,17-20H2 |
| InChiKey | IXEPQJQQSLMESJ-UHFFFAOYSA-N |
| CID | 72201045 |
| Short Description | Fbxo3 inhibitor |
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