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DPTIP hydrochloride

Axon 3772
  • Parent CAS:  351353-48-5
Purity:  99%
  • Soluble in water, DMSO and EtOH
  • MF:  C21H18N2O3S.HCl
  • MW:  414.91

Description

DPTIP hydrochloride is a potent selective, metabolically stable, and brain-penetrant neutral sphingomyelinase 2 (nSMase2) inhibitor with an IC50 value of 30 nM.

More Information

Parent CAS No. 351353-48-5
Chemical Name 2,6-Dimethoxy-4-(5-phenyl-4-(thiophen-2-yl)-1H-imidazol-2-yl)phenol hydrochloride
SMILES C1=C(OC)C(O)=C(OC)C=C1C1=NC(C2C=CC=CC=2)=C(C2SC=CC=2)N1.Cl
MFCD N.A.
InChi InChI=1S/C21H18N2O3S.ClH/c1-25-15-11-14(12-16(26-2)20(15)24)21-22-18(13-7-4-3-5-8-13)19(23-21)17-9-6-10-27-17;/h3-12,24H,1-2H3,(H,22,23);1H
InChiKey JXCSNAONSJHTTR-UHFFFAOYSA-N
CID 145887598
Short Description N-SMase2 inhibitor

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