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Norastemizole
- Tecastemizole
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C19H21FN4
- MW: 324.4
Description
Norastemizole is a histamine H1 receptor antagonist. Norastemizole is 13- to 16-fold more potent as an H1 antagonist than astemizole and 20- to 40-fold more potent in inhibiting histamine-induced bronchoconstriction.
More Information
| Parent CAS No. | 75970-99-9 |
|---|---|
| Chemical Name | 1-(4-Fluorobenzyl)-N-(piperidin-4-yl)-1H-benzo[d]imidazol-2-amine |
| SMILES | C1C(CN2C(NC3CCNCC3)=NC3C=CC=CC2=3)=CC=C(F)C=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C19H21FN4/c20-15-7-5-14(6-8-15)13-24-18-4-2-1-3-17(18)23-19(24)22-16-9-11-21-12-10-16/h1-8,16,21H,9-13H2,(H,22,23) |
| InChiKey | SFOVDSLXFUGAIV-UHFFFAOYSA-N |
| CID | 123618 |
| Short Description | H1 antagonist |
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