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UNC7467
Axon 3678
CAS:
2922283-43-8
Purity:
98%
- Soluble in DMSO
- MF: C20H13NO3
- MW: 315.32
Description
UNC7467 is a potent IP6K inhibitor with IC50 values of 8.9 nM, 4.9 nM and 1320 nM for IP6K1, IP6K2 and IP6K3, respectively. In vivo, UNC7467 reduced body weight gain in the context of a high-fat diet, decreased fat, ameliorated hepatic steatosis, and improved glycemic profiles in diet-induced obese mice.
More Information
| Parent CAS No. | 2922283-43-8 |
|---|---|
| Chemical Name | 3-(Biphenyl-4-yl)benzo[c]isoxazole-5-carboxylic acid |
| SMILES | C12=NOC(C3C=CC(C4C=CC=CC=4)=CC=3)=C1C=C(C(O)=O)C=C2 |
| MFCD | N.A. |
| InChi | InChI=1S/C20H13NO3/c22-20(23)16-10-11-18-17(12-16)19(24-21-18)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12H,(H,22,23) |
| InChiKey | FGCSKRKOSIKUGT-UHFFFAOYSA-N |
| CID | 164887496 |
| Short Description | IP6K inhibitor |
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