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RP 70676
Axon 3554
CAS:
136609-26-2
Purity:
99%
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C25H28N4S
- MW: 416.58
Description
RP 70676 is a potent and orally bioavailable inhibitor of acyl-CoA:cholesterol O-acyl transferase (ACAT) with IC50 values of 25 and 44 nM for rat and rabbit ACAT, respectively.
More Information
| Parent CAS No. | 136609-26-2 |
|---|---|
| Chemical Name | 1-(5-(4,5-Diphenyl-1H-imidazol-2-ylthio)pentyl)-3,5-dimethyl-1H-pyrazole |
| SMILES | C1(C2C=CC=CC=2)N=C(SCCCCCN2C(C)=CC(C)=N2)NC=1C1C=CC=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C25H28N4S/c1-19-18-20(2)29(28-19)16-10-5-11-17-30-25-26-23(21-12-6-3-7-13-21)24(27-25)22-14-8-4-9-15-22/h3-4,6-9,12-15,18H,5,10-11,16-17H2,1-2H3,(H,26,27) |
| InChiKey | UUPITLNVYVCTFW-UHFFFAOYSA-N |
| CID | 9844830 |
| Short Description | ACAT inhibitor |
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