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FBPase-1 inhibitor
- FBPase-1 inhibitor compound 1
Axon 3439
CAS:
883973-99-7
Purity:
99%
- Soluble in DMSO
- MF: C13H7Cl3N2O3S
- MW: 377.63
Description
FBPase-1 inhibitor compound 1 is an allosteric inhibitor of fructose-1,6-bisphosphatase (FBPase-1) with an IC50 value of 3.4 μM.
More Information
| Parent CAS No. | 883973-99-7 |
|---|---|
| Chemical Name | 2,5-Dichloro-N-(5-chlorobenzo[d]oxazol-2-yl)benzenesulfonamide |
| SMILES | C1(Cl)C=C2N=C(NS(=O)(=O)C3C=C(Cl)C=CC=3Cl)OC2=CC=1 |
| MFCD | MFCD22581250 |
| InChi | InChI=1S/C13H7Cl3N2O3S/c14-7-2-4-11-10(5-7)17-13(21-11)18-22(19,20)12-6-8(15)1-3-9(12)16/h1-6H,(H,17,18) |
| InChiKey | JCXZHFCBNFFHRC-UHFFFAOYSA-N |
| CID | 6102820 |
| Short Description | FBPase-1 inhibitor |
References
- C Lai et al. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1807-10.
- TW von Geldern et al. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1811-5.
