Bulk Inquiry
N-Desmethylclozapine
- Norclozapine - Normethylclozapine - ACP-104
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C17H17ClN4
- MW: 312.8
Description
Major metabolite of Clozapine (Axon 1146). N-Desmethylclozapine is a relatively potent and efficacious partial agonist at the D2 and D3 dopamine receptors, while showing inverse agonism at the 5-HT2A receptor. Moreover, N-Desmethylclozapine is a potent partial agonist at the muscarinic M1 receptor and a selective agonist at δ opioid receptor.
More Information
| Parent CAS No. | 6104-71-8 |
|---|---|
| Chemical Name | 8-Chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine |
| SMILES | N1C2C=CC=CC=2C(N2CCNCC2)=NC2C=C(Cl)C=CC1=2 |
| MFCD | MFCD00210189 |
| InChi | InChI=1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2 |
| InChiKey | JNNOSTQEZICQQP-UHFFFAOYSA-N |
| CID | 135409468 |
| Short Description | Clozapine metabolite |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1146 | Clozapine |
From $55.00 |
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| 1148 | GMC 1-169 |
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| 2796 | Clozapine N-oxide |
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