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Odiparcil

 - SB 424323  - GSK 424323
Axon 1536
CAS:  137215-12-4
  • Optical Purity:  Optically pure
  • Soluble in DMSO
  • MF:  C15H16O6S
  • MW:  324.35

Description

Odiparcil (SB424323) is an orally active beta-D-xyloside derivative that modulates glycosaminoglycan synthesis and has been studied for antithrombotic pharmacology.

By acting as a primer for glycosaminoglycan chain formation, odiparcil can alter proteoglycan metabolism and coagulation-associated pathways. It is relevant for research on thrombosis, dermatan sulfate biology and glycosaminoglycan handling in disease models.

Key Features

  • Orally active modulator of glycosaminoglycan (GAG) synthesis
  • Beta-D-xyloside pharmacology affecting proteoglycan metabolism
  • Studied for antithrombotic effects with limited hemorrhagic liability
  • Useful tool for dermatan sulfate and coagulation pathway research

Applications

  • Thrombosis and coagulation research
  • Glycosaminoglycan biosynthesis studies
  • Proteoglycan metabolism assays
  • Lysosomal storage and mucopolysaccharidosis model research

More Information

Parent CAS No. 137215-12-4
Chemical Name 7-((2R,3R,4S,5S)-tetrahydro-3,4,5-trihydroxy-2H-thiopyran-2-yloxy)-4-methyl-2H-chromen-2-one
SMILES [C@@H]1(O)[C@@H](O)[C@H](OC2C=C3OC(=O)C=C(C)C3=CC=2)SC[C@H]1O |&1:0,2,4,20,r|
MFCD N.A.
InChi InChI=1S/C15H16O6S/c1-7-4-12(17)21-11-5-8(2-3-9(7)11)20-15-14(19)13(18)10(16)6-22-15/h2-5,10,13-16,18-19H,6H2,1H3/t10-,13+,14-,15-/m1/s1
InChiKey JRHNIQQUVJOPQC-AQNFWKISSA-N
CID 216385
Short Description Anti-thrombotic

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