MST1R

MST1R

The MST1R (also known as RON) receptor tyrosine kinase (RTK) is a member of the c-Met family of RTKs that is expressed in epithelial cells and terminally-differentiated macrophages. MST1R is overexpressed in numerous solid tumors including breast, prostate, pancreas, and more with strong oncogenic function elicited through various signaling mechanisms.

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    LY 2801653
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More About MST1R

The MST1R (also known as RON) receptor tyrosine kinase (RTK) is a member of the c-Met family of RTKs that is expressed in epithelial cells and terminally-differentiated macrophages. MST1R is overexpressed in numerous solid tumors including breast, prostate, pancreas, and more with strong oncogenic function elicited through various signaling mechanisms[1].

[1] BG Hunt et al. MST1R (RON) expression is a novel prognostic biomarker for metastatic   progression in breast cancer patients. Breast Cancer Res Treat. 2020 Jun;181(3):529-540.
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