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Golgicide A - GCA

Based on 37 reference(s) in Google Scholar 8 10 37

Axon 4197

CAS [1139889-93-2]

MF C17H14F2N2
MW 284.30

  • Purity: 99%
  • Optical purity: 96% d.e.
  • Soluble in 0.1N HCl(aq), DMSO and EtOH

Golgicide A

Description

Golgicide A is a potent, highly specific, rapidly reversible inhibitor of the cis-Golgi ArfGEF GBF1. Inhibition of GBF1 function resulted in rapid dissociation of COPI vesicle coat from Golgi membranes and subsequent disassembly of the Golgi and trans-Golgi network.

Keywords: Golgicide A | Supplier | GBF1 inhibitor | GCA | CAS [1139889-93-2] | [1005036-73-6 ] | GTP | Arf | Inhibitor | Enzymes | ADP ribosylation factor 1 | Arf1 | Golgi BFA resistance factor 1

Potent, highly specific and reversible inhibitor of GBF1

Chemical name

rel-(3aR,9bS)-6,8-Difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline

Parent CAS No.

[1139889-93-2]

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10 mg €95.00 In Stock
50 mg €380.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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