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Axon 4088
CAS [1446321-46-5]
MF C19H19N3O3MW 337.37
Voxelotor is a first-in-class, potent and orally bioavailable allosteric effector of sickle cell hemoglobin (HbS). Voxelotor increases the affinity of hemoglobin for oxygen and consequently inhibits its polymerization when subjected to hypoxic conditions.
Keywords: Voxelotor | Supplier | HbS effector | GBT440 | GBT 440 | GBT-440 | Oxbryta | CAS [1446321-46-5] | [1667717-41-0] | Oxygen | HbS | Effector | Proteins | Sickle cell disease | Hemoglobin oxygen-affinity modulator
2-Hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
[1446321-46-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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