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JC2-11
Axon 3839
CAS:
937820-89-8
Purity:
98%
- Soluble in DMSO and EtOH
- MF: C17H15FO4
- MW: 302.3
Description
JC2-11 is an inhibitor of the NLRP3/NLRC4/AIM2 inflammasomes. JC2-11 inhibited the priming step and attenuated NLRP3, NLRC4, AIM2, and NC inflammasome activation by inhibiting ROS production and caspase-1 activity.
More Information
| Parent CAS No. | 937820-89-8 |
|---|---|
| Chemical Name | (E)-1-(3-Fluoro-4-methoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one |
| SMILES | C1C=C(/C=C/C(C2C=CC(OC)=C(F)C=2)=O)C=C(OC)C=1O |
| MFCD | N.A. |
| InChi | InChI=1S/C17H15FO4/c1-21-16-8-5-12(10-13(16)18)14(19)6-3-11-4-7-15(20)17(9-11)22-2/h3-10,20H,1-2H3/b6-3+ |
| InChiKey | YYAIFDXWRNNHAW-ZZXKWVIFSA-N |
| CID | 24895134 |
| Short Description | NLRP3/NLRC4/AIM2 inhibitor |
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