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(+)-Abscisic acid
- ABA
Axon 3755
CAS:
21293-29-8
- Optical Purity: Optically pure
- Soluble in 0.1N NaOH(aq), DMSO and EtOH
- MF: C15H20O4
- MW: 264.32
Description
The phytohormone (+)-Abscisic acid is a ligand of lanthionine synthetase C-like 2 (LANCL2) and targets cells of the innate immune response, mesenchymal and hemopoietic stem cells and cells involved in the regulation of systemic glucose homeostasis.
More Information
| Parent CAS No. | 21293-29-8 |
|---|---|
| Chemical Name | (2Z,4E)-5-((S)-1-Hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-enyl)-3-methylpenta-2,4-dienoic acid |
| SMILES | C1C(C)(C)[C@@](O)(/C=C/C(/C)=CC(=O)O)C(C)=CC1=O |&1:4,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 |
| InChiKey | JLIDBLDQVAYHNE-YKALOCIXSA-N |
| CID | 5280896 |
| Short Description | LANCL2 ligand |
References
- L Sturla et al. LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells. J Biol Chem. 2009 Oct 9;284(41):28045-28057.
- A Carbo et al. An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease. J Med Chem. 2016 Nov 23;59(22):10113-10126.
- C Fresia et al. G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2. Sci Rep. 2016 May 25;6:26658.
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