GSK484 hydrochloride

Based on 16 reference(s) in Google Scholar 8 10 16

Axon 3531

CAS [1652591-81-5]

MF C27H31N5O3.HCl
MW 510.03

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in water, DMSO and EtOH
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GSK484 hydrochloride

Description

GSK484 hydrochloride is a highly potent, selective, and reversible PAD4 inhibitor with an IC50 value of 50 nM (in the absence of calcium).

KEYWORDS: GSK484 hydrochloride | Supplier | PAD4 inhibitor | GSK 484 hydrochloride | GSK-484 hydrochloride | CAS [1652591-81-5] | [1652629-23-6] | Protein L-arginine | PAD | Inhibitor | Enzymes | Immunology | NETosis | PADI4 | Oncology | Neutrophil extracellular traps | Innate immunity | Protein arginine deiminase

Highly potent, selective, and reversible PAD4 inhibitor

Chemical name

((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride

Parent CAS No.

[1652629-23-6]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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