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DSRM-3716
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C9H6IN
- MW: 255.06
Description
DSRM-3716 is a potent and selective inhibitor of SARM1 NADase (IC50 value of 75 nM) that recapitulates the SARM1-/- phenotype and protects axons from degeneration induced by axotomy or mitochondrial dysfunction.
More Information
| Parent CAS No. | 58142-99-7 |
|---|---|
| Chemical Name | 5-Iodoisoquinoline |
| SMILES | C1C=C2C(I)=CC=CC2=CN=1 |
| MFCD | MFCD11226893 |
| InChi | InChI=1S/C9H6IN/c10-9-3-1-2-7-6-11-5-4-8(7)9/h1-6H |
| InChiKey | CUILFTFMBBGSFT-UHFFFAOYSA-N |
| CID | 11391181 |
| Short Description | SARM1 NADase inhibitor |
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