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Axon 3480
CAS [2765218-56-0]
MF C16H15N3O2SMW 313.37
PY-60 is a robust and specific activator of YAP transcriptional activity by targeting annexin A2 (Kd value of 1.4 µM). PY-60 treatment liberates annexin A2 (ANXA2) from the membrane, ultimately promoting a phosphatase-bound, nonphosphorylated and transcriptionally active form of YAP.
KEYWORDS: PY-60 | Supplier | YAP activator | YAP activator PY-60 | PY 60 | PY60 | CAS [2765218-56-0] | Hippo signaling pathway | YAP | Activator | Transcription Factors | Yes-associated protein 1 | Regenerative repair | Hippo-YAP pathway | TEAD
5-Phenyl-N-(3-(thiazol-2-yl)propyl)isoxazole-3-carboxamide
[2765218-56-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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