PY-60 - YAP activator PY-60

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3480

CAS [2765218-56-0]

MF C16H15N3O2S
MW 313.37

  • Purity: 98%
  • Soluble in DMSO and EtOH



PY-60 is a robust and specific activator of YAP transcriptional activity by targeting annexin A2 (Kd value of 1.4 µM). PY-60 treatment liberates annexin A2 (ANXA2) from the membrane, ultimately promoting a phosphatase-bound, nonphosphorylated and transcriptionally active form of YAP.

KEYWORDS: PY-60 | Supplier | YAP activator | YAP activator PY-60 | PY 60 | PY60 | CAS [2765218-56-0] | Hippo signaling pathway | YAP | Activator | Transcription Factors | Yes-associated protein 1 | Regenerative repair | Hippo-YAP pathway | TEAD

Size Unit Price Stock
5 mg €150.00 In Stock
25 mg €530.00 In Stock
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Size Unit Price Stock
2 x 5 mg €240.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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