Simvastatin - MK733 | Synvinolin

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3443

CAS [79902-63-9]

MF C25H38O5
MW 418.57

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO and EtOH

Simvastatin

Description

Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.2 nM.

WC Duane et al. Simvastatin, a competitive inhibitor of HMG-CoA reductase, lowers cholesterol saturation index of gallbladder bile. Hepatology. 1988 Sep-Oct;8(5):1147-50.

EE Slater et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs. 1988;36 Suppl 3:72-82.

Inhibitor of HMG-CoA reductase

Chemical name

(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate

Parent CAS No.

[79902-63-9]

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Simvastatin - MK733 | Synvinolin

Description

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