Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3435

CAS [1175940-86-9]

MF C16H19N3O5S2
MW 397.47

  • Purity: 99%
  • Optical purity: 100% e.e.
  • Soluble in DMSO and EtOH



(S)-VU0637120 is a first-in-class, selective neuropeptide Y4 receptor allosteric antagonist with an IC50 value of 2.7 μM. (S)-VU0637120 selectively inhibits native Y4R function and binds in an allosteric site located below the binding pocket of the endogenous ligand pancreatic polypeptide in the core of the Y4R transmembrane domains.

KEYWORDS: (S)-VU0637120 | Supplier | Y4R allosteric antagonist | (S)-VU 0637120 | (S)-VU-0637120 | CAS [1175940-86-9] | Neuropeptide Y | Antagonist | Receptors | Metabolic disease | Anorexia | Obesity

First-in-class, selective neuropeptide Y4 receptor allosteric antagonist

Chemical name


Parent CAS No.


Size Unit Price Stock
5 mg €120.00 In Stock
25 mg €420.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €200.00 In Stock
2 x 25 mg €640.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...