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Terbinafine
- SF86-327
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C21H25N
- MW: 291.43
Description
Terbinafine is an orally active antifungal agent inhibiting fungal squalene epoxidase.
More Information
| Parent CAS No. | 91161-71-6 |
|---|---|
| Chemical Name | (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine |
| SMILES | C1C=C2C(CN(C)C/C=C/C#CC(C)(C)C)=CC=CC2=CC=1 |
| MFCD | MFCD00242672 |
| InChi | InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+ |
| InChiKey | DOMXUEMWDBAQBQ-WEVVVXLNSA-N |
| CID | 1549008 |
| Short Description | Antifungal agent |
References
- A Stütz et al. Synthesis and antifungal activity of (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphtha lenemethanamine (SF 86-327) and related allylamine derivatives with enhanced oral activity. J Med Chem. 1984 Dec;27(12):1539-43.
- S Shadomy et al. In-vitro studies with SF 86-327, a new orally active allylamine derivative. Sabouraudia. 1985 Apr;23(2):125-32.
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