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Deferasirox
- ICL670
Axon 3375
CAS:
201530-41-8
Purity:
100%
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C21H15N3O4
- MW: 373.36
Description
Deferasirox is an orally active iron chelator. Deferasirox was found to demonstrate a two- to fivefold higher potency than deferoxamine in mobilizing tissue iron and promoting its excretion in various in vitro and in vivo models. ICL670 is highly selective for iron and does not induce the excretion of zinc or copper.
More Information
| Parent CAS No. | 201530-41-8 |
|---|---|
| Chemical Name | 4-(3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid |
| SMILES | N1(C2C=CC(C(O)=O)=CC=2)N=C(C2C=CC=CC=2O)N=C1C1C(O)=CC=CC=1 |
| MFCD | MFCD09951804 |
| InChi | InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,25-26H,(H,27,28) |
| InChiKey | BOFQWVMAQOTZIW-UHFFFAOYSA-N |
| CID | 214348 |
| Short Description | Iron chelator |
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