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TH1760
Axon 3285
CAS:
2567914-01-4
Purity:
98%
- Soluble in DMSO
- MF: C20H18N4O5S
- MW: 426.45
Description
TH1760 is a first-in-class, potent, selective and cell-active NUDT15 (MTH2) inhibitor with an IC50 value of 25 nM.
More Information
| Parent CAS No. | 2567914-01-4 |
|---|---|
| Chemical Name | 6-(4-(1H-Indole-5-carbonyl)piperazin-1-ylsulfonyl)benzo[d]oxazol-2(3H)-one |
| SMILES | C12OC(=O)NC=1C=CC(S(=O)(=O)N1CCN(C(=O)C3C=CC4NC=CC=4C=3)CC1)=C2 |
| MFCD | N.A. |
| InChi | InChI=1S/C20H18N4O5S/c25-19(14-1-3-16-13(11-14)5-6-21-16)23-7-9-24(10-8-23)30(27,28)15-2-4-17-18(12-15)29-20(26)22-17/h1-6,11-12,21H,7-10H2,(H,22,26) |
| InChiKey | HNCVDRFFJZJQRW-UHFFFAOYSA-N |
| CID | 146048072 |
| Short Description | NUDT15 inhibitor |
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