6-Thioguanine

Based on 4478 reference(s) in Google Scholar 8 10 4478

Axon 3253

CAS [154-42-7]

MF C5H5N5S
MW 167.19

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq) and DMSO

6-Thioguanine

Description

6-Thioguanine, a thiopurine-derivative, is metabolized in active forms which are incorporated into RNA and DNA, respectively, as fraudulent bases. Incorporation into DNA results into a stop of replication by single-strand breaks, crosslinking and sister chromatid exchange. Immunosuppresant.

KEYWORDS: 6-Thioguanine | supplier | Purine analog | CAS [154-42-7] | [76078-67-6] | Immunology | Non Selective | Suppresant | Antimetabolite drug | Leukemia | Immune-inflammatory disease | Psoriasis | SLE | Polycythemia vera | Churg-Strauss syndrome | IBD | Collagenous sprue | Refractory celiac disease | Autoimmune hepatitis

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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