Montelukast sodium - MK-0476

Based on 2490 reference(s) in Google Scholar 8 10 2490

Axon 3236

CAS [151767-02-1]

MF C35H35ClNNaO3S
MW 608.17

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water and DMSO
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Montelukast sodium

Description

Montelukast sodium is a potent and selective leukotriene D4 receptor antagonist with excellent in vivo activity. Montelukast sodium shows Ki values for [3H]leukotriene D4 specific binding of 0.18 nM, 4 nM and 0.52 nM in guinea pig lung, sheep lung and dimethylsulfoxide-differentiated U937 cell plasma membrane preparations, respectively.

KEYWORDS: Montelukast sodium | supplier | CysLT1 antagonist | MK-0476 | MK0476 | MK 0476 | CAS [151767-02-1] | [158966-92-8] | Cysteinyl leukotrienes | CysLT | Antagonist | Receptors | Asthma

Potent and selective CysLT1 receptor antagonist

Chemical name

Sodium (R,E)-2-(1-((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)methyl)cyclopropyl)acetate

Parent CAS No.

[158966-92-8]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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