Gemcitabine hydrochloride - dFdC | LY 188011 | 2’,2’‑difluorodeoxycytidine

Based on 17099 reference(s) in Google Scholar 8 10 17099

Axon 3233

CAS [122111-03-9]

MF C9H11F2N3O4.HCl
MW 299.66

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water and DMSO
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Gemcitabine hydrochloride

Description

Gemcitabine hydrochloride, a deoxycytidine analogue, is an antimetabolite and a specific inhibitor of DNA synthesis. Gemcitabine hydrochloride exhibits good activity against human leukemic cell lines and murine solid tumors Moreover, Gemcitabine hydrochloride has shown activity against a wide spectrum of human solid tumors including nonsmall cell lung, pancreatic, colon, breast, bladder, ovarian, head and neck, cervical and hepatocellular cancers.

KEYWORDS: Gemcitabine hydrochloride | supplier | DNA synthesis inhibitor | dFdC | 2’ | 2’-difluorodeoxycytidine | LY 188011 | LY188011 | LY-188011' | CAS [122111-03-9] | [95058-81-4] | DNA-RNA | DNA synthesis | Inhibitor

Specific inhibitor of DNA synthesis; Antimetabolite

Chemical name

4-Amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride

Parent CAS No.

[95058-81-4]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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