Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3210

CAS [2649154-57-2]

MF C30H25ClN4O7
MW 589.00

  • Purity: 99%
  • Optical purity: 98.4% e.e.
  • Soluble in DMSO



RA375 is a potent RPN13 inhibitor with IC50 values of 13 and 26 nM against HeLa and SKOV3 cells, respectively. Treatment with RA375 caused a rapid and profound accumulation of high molecular weight polyubiquitinated proteins and reduced intracellular glutathione levels, which produce endoplasmic reticulum and oxidative stress, and trigger apoptosis.

KEYWORDS: RA375 | Supplier | RPN13 inhibitor | RA 375 | RA-375 | CAS [2649154-57-2] | Non Selective (Ubiquitin peptides) | RPN | Inhibitor | Receptors | Ovarian tumor | Ubiquitin receptor

Size Unit Price Stock
5 mg €180.00 In Stock
25 mg €680.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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