SBI-183

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3209

CAS [625403-59-0]

MF C18H20N2O2
MW 296.36

  • Purity: 99%
  • Soluble in DMSO and EtOH
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SBI-183

Description

SBI-183 is an orally active inhibitor of QSOX1 (Kd value of 20 μM), thereby suppressing the proliferative and invasive phenotype of two renal cancer cell lines (786-O and RCJ-41T2), a triple negative breast cancer (TNBC) cell line (MDA-MB-231), a lung adenocarcinoma cell line (A549), and a pancreatic ductal adenocarcinoma (MIA PaCa2). Moreover, SBI-183 inhibits tumor growth in two independent human xenograft mouse models of renal cell carcinoma.

KEYWORDS: SBI-183 | Supplier | QSOX1 inhibitor | SBI183 | SBI 183 | CAS [625403-59-0] | Non Selective (Thiols) | Thiol | Inhibitor | Enzymes

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10 mg €110.00 In Stock
50 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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