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Axon 3209
CAS [625403-59-0]
MF C18H20N2O2MW 296.36
SBI-183 is an orally active inhibitor of QSOX1 (Kd value of 20 μM), thereby suppressing the proliferative and invasive phenotype of two renal cancer cell lines (786-O and RCJ-41T2), a triple negative breast cancer (TNBC) cell line (MDA-MB-231), a lung adenocarcinoma cell line (A549), and a pancreatic ductal adenocarcinoma (MIA PaCa2). Moreover, SBI-183 inhibits tumor growth in two independent human xenograft mouse models of renal cell carcinoma.
KEYWORDS: SBI-183 | Supplier | QSOX1 inhibitor | SBI183 | SBI 183 | CAS [625403-59-0] | Non Selective (Thiols) | Thiol | Inhibitor | Enzymes
3-Methoxy-N-(4-(pyrrolidin-1-yl)phenyl)benzamide
[625403-59-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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