ERAP1 inhibitor compound 3

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3208

CAS [865273-97-8]

MF C20H21F3N2O5S
MW 458.45

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq) and DMSO

ERAP1 inhibitor compound 3

Description

ERAP1 inhibitor compound 3 allosterically activates endoplasmic reticulum aminopeptidase 1 (ERAP1) hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activity toward a nonamer peptide representative of physiological substrates (EC50 value of 0.4 μM). ERAP1 inhibitor compound 3 inhibits ERAP1’s activity in a cellular antigen processing assay with an IC50 value of 1.0 μM.

KEYWORDS: ERAP1 inhibitor compound 3 | supplier | ERAP1 inhibitor | CAS [865273-97-8] | Peptides (Endoplasmatic reticulum) | ERAP | Inhibitor | Enzymes | ARTS1 | ALAP | ERAAP | PILS-AP | Autoimmune disease

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5 mg €160.00 In Stock
25 mg €560.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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