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UCM-05194 ammonium salt

Axon 3207
  • Parent CAS:  2411412-36-5
  • Optical Purity:  Optically pure
  • Soluble in water, DMSO and EtOH
  • MF:  C19H30BrO6P.NH3
  • MW:  482.35

Description

UCM-05194 is a potent and selective type 1 lysophosphatidic acid (LPA1) receptor agonist with an EC50 value of 0.24 μM and a KD value of 19.6 nM. UCM-05194 induces characteristic LPA1-mediated cellular effects and prompts the internalization of the receptor leading to its functional inactivation in primary sensory neurons and to an efficacious attenuation of the pain perception in an in vivo model of neuropathic pain.

More Information

Parent CAS No. 2411412-36-5
Chemical Name (S)-1-Bromo-3-(phosphonooxy)propan-2-yl 10-phenyldecanoate ammonium salt
SMILES C1C=CC(CCCCCCCCCC(=O)O[C@H](CBr)COP(O)(O)=O)=CC=1.N |&1:16,r|
MFCD N.A.
InChi InChI=1S/C19H30BrO6P.H3N/c20-15-18(16-25-27(22,23)24)26-19(21)14-10-5-3-1-2-4-7-11-17-12-8-6-9-13-17;/h6,8-9,12-13,18H,1-5,7,10-11,14-16H2,(H2,22,23,24);1H3/t18-;/m1./s1
InChiKey UKZAXCXBQFDZCW-GMUIIQOCSA-N
CID 156600284
Short Description LPA1 agonist

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