UCM-05194 ammonium salt

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3207

CAS [N.A.]

MF C19H30BrO6P.NH3
MW 482.35

  • Purity: 97%
  • Optical purity: Optically pure
  • Soluble in water, DMSO and EtOH
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UCM-05194 ammonium salt

Description

UCM-05194 is a potent and selective type 1 lysophosphatidic acid (LPA1) receptor agonist with an EC50 value of 0.24 μM and a KD value of 19.6 nM. UCM-05194 induces characteristic LPA1-mediated cellular effects and prompts the internalization of the receptor leading to its functional inactivation in primary sensory neurons and to an efficacious attenuation of the pain perception in an in vivo model of neuropathic pain.

KEYWORDS: UCM-05194 ammonium salt | Supplier | LPA1 agonist | UCM05194 | UCM 05194 | CAS [2411412-36-5] | LPA | LPA1 | Agonist | Receptors | Neuropathic pain

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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