ML2-SA1 - EVP-22

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2980

CAS [N.A.]

MF C14H13Cl2NO
MW 282.17

  • Purity: 100%
  • Soluble in DMSO



ML2-SA1 is a potent, selective and efficacious activator of TRPML2 with EC50 values of 1.24 μM and 2.38 μM for human and mouse TRPML2, respectively. ML2-SA1 shows high selectivity over h/mTRPML1 and h/mTRPML3 in both calcium imaging and endolysosomal patch-clamp experiments and it does not activate TPC1 nor TPC2.

KEYWORDS: ML2-SA1 | supplier | TRPML2 activator | EVP-22 | ML2SA1 | ML2 SA1 | EVP22 | EVP 22 | CAS [N.A.] | Non Selective (Cations) | TRPML | Activator | Ion Channels | MCOLN2 | Innate immune response

Size Unit Price Stock
10 mg €105.00 In Stock
50 mg €350.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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