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JNJ 47965567

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2890

CAS [1428327-31-4]

MF C28H32N4O2S
MW 488.64

  • Purity: 99%
  • Soluble in DMSO

JNJ 47965567

Description

Highly potent and brain penetrant P2X7 antagonist in human, rat, and mouse cell lines (pKi values of 7.9, 7.9 and 6.9 for human, rat, and human whole blood P2X7). Probe compound for the preclinical assessment of P2X7 blockade in animal models of neuro-inflammation. DMPK properties suitable for preclinical pharmacodynamics studies.

Keywords: JNJ 47965567 | supplier | P2X7 antagonist | JNJ47965567 | JNJ-47965567 | CAS [1428327-31-4] | Non Selective (Cations) | P2X7 | Antagonist | Ion Channels | Brain Penetrant | Neuro-inflammation

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Size Unit Price Stock
10 mg €130.00 In Stock
50 mg €480.00 In Stock
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2 x 10 mg €200.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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