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Axon 2874
CAS [1187856-49-0]
MF C23H26ClNO5MW 431.91
Ralinepag is an orally bioavailable, non-prostanoid IP receptor agonist (EC50 value of 8.5 nM, human IP receptor assay) that is efficacious in the rat MCT model of pulmonary arterial hypertension. It has good selectivity in both binding and functional assays with respect to most members of the prostanoid receptor family, but a more modest 30-50-fold selectivity over the EP3 receptor.
KEYWORDS: Ralinepag | supplier | IP agonist | APD 811 | APD811 | APD-811 | CAS [1187856-49-0] | [1187856-43-4] | Prostaglandins | PGI2 (IP) | Agonist | Receptors | EP3 receptor
2-(((1r,4r)-4-((Phenyl(p-tolyl)carbamoyloxy)methyl)cyclohexyl)methoxy) acetic acid
[1187856-49-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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