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Featured Products
Axon 2737
CAS [496807-64-8]
MF C22H12ClF3N2O4MW 460.79
EN460, an inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50 value of 1.9 μM). Despite rapid and promiscuous reactivity with thiolates, EN460 exhibits selectivity for ERO1.
KEYWORDS: EN460 | supplier | ERO1 inhibitor | ERO1 Inhibitor II | EN 460 | EN-460 | CAS [496807-64-8] | Protein Disulfide Isomerase (PDI) | ERO1 | Inhibitor | Enzymes | Endoplasmic Reticulum Oxidation
(Z)-2-Chloro-5-(5-oxo-4-((5-phenylfuran-2-yl)methylene)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
[496807-64-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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