Based on 2 reference(s) in Google Scholar 9 10 2

Axon 2544

CAS [890888-12-7]

MF C19H25N5
MW 323.44

  • Purity: 99%
  • Soluble in DMSO



Suppressor of superoxide production from mitochondrial complex III (IC50 value 1.7 µM against superoxide production mediated by the outer Q-binding site of complex III (site IIIQo)). S3QEL-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells, and strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets. S3QEL-2 modulates HIF-1α activation without directly affecting metabolism.

KEYWORDS: S3QEL 2 | supplier | Complex III modulator | S3QEL2 | CAS [890888-12-7] | Quinol | Complex III | Coenzyme Q | superoxide | ROS | mitochondria | Q-binding site | site III Qo | oxidative stress | reactive oxygen species

Size Unit Price Stock
10 mg €60.00 In Stock
50 mg €210.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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