BX 430

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2523

CAS [688309-70-8]

MF C15H15Br2N3O
MW 413.11

  • Purity: 99%
  • Soluble in DMSO

BX 430


Noncompetitive, allosteric antagonist of human P2X4 receptor channels (IC50 value 0.54 μM as determined by Patch-clamp electrophysiology) with 10-100 fold selectivity over P2X1–P2X3, P2X5, and P2X7. A useful molecular probe to assess the specific role of P2X4 in inflammatory and neuropathic conditions, where ATP signaling has been shown to be dysfunctional. BX430 has no effect on mouse and rat P2X4Rs.

KEYWORDS: BX 430 | supplier | P2X4 antagonist | BX430 | CAS [688309-70-8] | Calcium | P2X4 | Ion Channel | P2X | cation | inflammation | ATP | pain | purinoceptor | vasodilation | patch clamp | current

Size Unit Price Stock
10 mg €105.00 In Stock
50 mg €375.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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