iMDK

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2258

CAS [881970-80-5]

MF C21H13FN2O2S
MW 376.40

  • Purity: 99%
  • Soluble in DMSO

iMDK

Description

MDK expression inhibitor; iMDK inhibits specifically and dose-dependently the expression of Midkine (MDK) in H441 lung adenocarcinoma cells, but does not inhibit PTN (Pleiotrophin), which has considerable homology to MDK. iMDK induces apoptotosis in MDK-expressing H441 lung adenocarcinoma cells by suppression of the PI3K/Akt pathway but not the MAPK pathway. iMDK does not inhibit another growth factor VEGF.

KEYWORDS: iMDK | Midkine expression inhibitor | CAS [881970-80-5] | NF-κB Pathway | Midkine | Inhibitor | Proteins | cytokine | NF-êB | PI3K | Akt | Apoptosis | Carcinoma | Lung cancer

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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €340.00 In Stock
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Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €560.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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