(R)-6-Hydroxybuspirone hydrochloride - BMS 442608 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1997

CAS [2108486-86-6]

MF C21H31N5O3.HCl
MW 437.96

  • Purity: 99%
  • Soluble in water and DMSO

(R)-6-Hydroxybuspirone hydrochloride


Optically pure (R)-enantiomer of 6-hydroxybuspirone (Axon 1996), a major active metabolite of Buspirone (Axon 1995); 5-HT1A partial agonist. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the (S)-enantiomer; while (S)-Enantiomer has advantage of being cleared more slowly from blood compared to the (R)-enantiomer

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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