Buspirone hydrochloride - Buspar

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1995

CAS [33386-08-2]

MF C21H31N5O2.HCl
MW 421.96

Purity: 100%
Soluble in water and DMSO

Buspirone hydrochloride

Description

Serotonin 5-HT1A receptor partial agonist; an anxiolytic psychoactive drug used primarily to treat generalized anxiety disorder (GAD); Suggestive evidence that buspirone reverses SSRI-induced sexual dysfunction

DA Ciraulo et al. Alterations in pharmacodynamics of anxiolytics in abstinent alcoholic men: Subjective responses, abuse liability, and electroencephalographic effects of alprazolam, diazepam, and buspirone. J. Clin. Pharmacol. 1997, 37(1), 64-73.

N Demartinis et al. Prior benzodiazepine use and buspirone response in the treatment of generalized anxiety disorder. J. Clin. Psychiatry 2000, 61(2), 91-94.

CNS 5-HT1A A19

5-HT1A partial agonist

Chemical name

8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride

Parent CAS No.

[36505-84-7]

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