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(-)-WAY 100135 dihydrochloride
- (R)-WAY 100135 dihydrochloride
Axon 1359
More Information
| Parent CAS No. | 133025-52-2 |
|---|---|
| Chemical Name | (R)-N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-2-phenyl-propionamide dihydrochloride |
| SMILES | N1(C2C=CC=CC=2OC)CCN(C[C@@H](C2C=CC=CC=2)C(=O)NC(C)(C)C)CC1.Cl.Cl |&1:13,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C24H33N3O2.2ClH/c1-24(2,3)25-23(28)20(19-10-6-5-7-11-19)18-26-14-16-27(17-15-26)21-12-8-9-13-22(21)29-4;;/h5-13,20H,14-18H2,1-4H3,(H,25,28);2*1H/t20-;;/m0../s1 |
| InChiKey | VJGZNBYDSDEOED-FJSYBICCSA-N |
| CID | 14801906 |
| Short Description | 5-HT1A antagonist |
References
- K Wedzony et al. WAY 100135, an Antagonist of 5-HT1A Serotonin Receptors, Attenuates Psychotomimetic Effects of MK-801. Neuropsychopharmacology 2000, 23, 547-559.
- KF Rhodes et al. The antagonist actions of WAY 100135 and its enantiomers on 5-HT1A receptor-mediated hyperpolarization of the rat isolated superior cervical ganglion. Naunyn-Schmiedeberg's Arch. Pharmacol. 1993, 348(3), 225-227.
- NA Escandon et al. Characterization of the serotonin1A receptor antagonist activity of WAY-100135 and spiperone. J. Pharmacol. Exp. Ther. 1994, 268, 441-447.
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