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Receptors
GPCR
Dopamine
D1
N 0924 hydrochloride

N 0924 hydrochloride - N 0924

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1039

CAS [125572-92-1]

MF C19H25NOS.HCl
MW 351.93

Purity: 100%
Optical purity: 98% ee
Soluble in water and DMSO

N 0924 hydrochloride

Description

Dopamine receptor agonist; less active enantiomer of N-0437 (Axon 1038) vs opposite (S)-(-)-enantiomer, Rotigotine (Axon 1040)

J van der Weide et al. Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734. Eur. J. Pharmacol. 1986, 125, 273-282.

M.Y. Splinter. Rotigotine: Transdermal Dopamine Agonist Treatment of Parkinson's Disease and Restless Legs Syndrome. Ann. Pharmacother. 2007, 41, 285-295.

Jenner et al. A novel dopamine agonist for the transdermal treatment of Parkinson’s disease. Neurology. 2005, 65, S3-S5.

CNS D2 D3 D4 D1 A17

Dopamine agonist; less active enantiomer of N-0437 (Axon 1038)

Chemical name

(R)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol hydrochloride

Parent CAS No.

[112835-48-0]

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