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5-Methoxy-N-propyl-2-aminotetraline hydrochloride
Axon 1025
- Parent CAS: 3899-07-8
Purity:
95%
- Soluble in water and DMSO
- MF: C14H21NO.HCl
- MW: 255.78
Description
5-Methoxy-N-propyl-2-aminotetraline hydrochloride is an aminotetralin chemical building block with no defined receptor or enzyme pharmacology assigned in the current product information. It is best positioned as a synthetic intermediate for monoaminergic ligand chemistry.
Methoxy-substituted aminotetralins are useful scaffolds in medicinal chemistry programs focused on dopamine, serotonin and other CNS-active ligands. This compound can support analogue preparation, scaffold diversification and structure-activity relationship work.
Key Features
- Aminotetralin chemical building block
- Methoxy-substituted CNS ligand scaffold
- No defined receptor or enzyme target assigned
- Supports analogue synthesis and SAR studies
Applications
- Medicinal chemistry synthesis
- Aminotetralin analogue preparation
- Monoaminergic ligand scaffold development
- Structure-activity relationship research
More Information
| Parent CAS No. | 3899-07-8 |
|---|---|
| Chemical Name | (5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine hydrochloride |
| SMILES | C1C=C2CC(NCCC)CCC2=C(OC)C=1.Cl |
| MFCD | MFCD10567059 |
| InChi | InChI=1S/C14H21NO.ClH/c1-3-9-15-12-7-8-13-11(10-12)5-4-6-14(13)16-2;/h4-6,12,15H,3,7-10H2,1-2H3;1H |
| InChiKey | ZOKTXMBBTXQAIC-UHFFFAOYSA-N |
| CID | 12581163 |
| Short Description | Building Block |
References
- L.A. van Vliet et al. Affinity for dopamine D2, D3, and D4 receptors of 2-aminotetralins. Relevance of D2 agonist binding for determination of receptor subtype selectivity. J. Med. Chem. 1996, 39, 4233-4237.
- A.S. Horn et al. Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release. J. Med. Chem. 1978, 21, 825-828.
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