Cytogenin
Axon N0043
CAS:
132971-59-6
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C11H10O5
- MW: 222.19
Description
Immunomodulative antitumor compound. Active as antitumor, immunomodulator, angiogenesis inhibitor, anti-inflammatory, anti-arthritic and anti-diabetic..******Source information: Streptoverticillium eurocidicum MI43-37F11
More Information
| Parent CAS No. | 132971-59-6 |
|---|---|
| SMILES | C1(OC)C=C2C=C(CO)OC(=O)C2=C(O)C=1 |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | Angiogenesis inhibitor, immunomodulator |
References
- H Kumagai et al. Cytogenin a novel antitumor substance. J Antibiot (Tokyo). 1990 Nov;43(11):1505-7.
- H Kumagai H, et al. Antitumor activity of cytogenin. J Antibiot (Tokyo). 1995 Feb;48(2):175-8.
- Yoshioka T, et al. Production of antibiotic MI43-37F11 and production intermediate. 1992, patent JPH04112884
- H Kumagai et al. Action of cytogenin on lymphoid cells and their cytokine production. J Antibiot (Tokyo). 1995 Apr;48(4):317-20.
- S Hirano et al. Effects of cytogenin, a novel anti-arthritic agent, on type II collagen-induced arthritis in DBA/1J mice and adjuvant arthritis in Lewis rats. Int J Tissue React. 1994;16(4):155-62.
- H Kumagai et al. Effect of cytogenin, a novel immunomodulator, on streptozotocin-induced diabetes in mice. J Antibiot (Tokyo). 2005 Mar;58(3):202-5.
- T Oikawa et al. Effects of cytogenin, a novel microbial product, on embryonic and tumor cell-induced angiogenic responses in vivo. Anticancer Res. 1997 May-Jun;17(3C):1881-6.
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