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Ralinepag
- APD 811- Soluble in DMSO
- MF: C23H26ClNO5
- MW: 431.91
Description
Ralinepag is an orally bioavailable, non-prostanoid IP receptor agonist (EC50 value of 8.5 nM, human IP receptor assay) that is efficacious in the rat MCT model of pulmonary arterial hypertension. It has good selectivity in both binding and functional assays with respect to most members of the prostanoid receptor family, but a more modest 30-50-fold selectivity over the EP3 receptor.
More Information
| Parent CAS No. | 1187856-49-0 |
|---|---|
| Chemical Name | 2-(((1r,4r)-4-((Phenyl(p-tolyl)carbamoyloxy)methyl)cyclohexyl)methoxy) acetic acid |
| MFCD | N.A. |
| Short Description | IP agonist |
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