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ZZW-115 trihydrochloride
- ICI738
Axon 3735
- Parent CAS: 801991-87-7
Purity:
99%
- Soluble in water and DMSO
- MF: C24H31F3N4S.3HCl
- MW: 573.97
Description
ZZW-115 trihydrochloride is a potent NUPR1 inhibitor (Kd value of 2.1 μM) which showed dose-dependent tumor regression with no neurological effects and an ability to induce cell death mainly by necroptosis.
More Information
| Parent CAS No. | 801991-87-7 |
|---|---|
| Chemical Name | N,N-Dimethyl-2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanamine trihydrochloride |
| SMILES | C1C=C2N(CCCN3CCN(CCN(C)C)CC3)C3C=C(C(F)(F)F)C=CC=3SC2=CC=1.Cl.Cl.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C24H31F3N4S.3ClH/c1-28(2)12-13-30-16-14-29(15-17-30)10-5-11-31-20-6-3-4-7-22(20)32-23-9-8-19(18-21(23)31)24(25,26)27;;;/h3-4,6-9,18H,5,10-17H2,1-2H3;3*1H |
| InChiKey | OBSKIDNFCBBXKJ-UHFFFAOYSA-N |
| CID | 25010688 |
| Short Description | NUPR1 inhibitor |
