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MCUF-651

Axon 3600
CAS:  2747162-85-0
Purity:  99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH
  • MF:  C17H22F2N4OS
  • MW:  368.44

Description

MCUF-651 is a selective and orally bioavailable PAM of guanylyl cyclase A receptor (GC-A) with an EC50 value of 0.45 µM in HEK293 GC-A cells. MCUF-651 exhibits therapeutic activity in human hypertension and heart failure ex vivo.

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