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AG-270
Axon 3515
CAS:
2201056-66-6
Purity:
98%
- Soluble in DMSO
- MF: C30H27N5O2
- MW: 489.57
Description
AG-270 is a first-in-class, highly potent, selective, orally bioavailable MAT2A inhibitor with an IC50 value of 0.014 μM.
More Information
| Parent CAS No. | 2201056-66-6 |
|---|---|
| Chemical Name | 3-Cyclohexenyl-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| SMILES | C1C=C(C2=C(NC3C=CC=CN=3)NC3=C(C4CCCCC=4)C(C4C=CC=CC=4)=NN3C2=O)C=CC=1OC |
| MFCD | N.A. |
| InChi | InChI=1S/C30H27N5O2/c1-37-23-17-15-21(16-18-23)26-28(32-24-14-8-9-19-31-24)33-29-25(20-10-4-2-5-11-20)27(34-35(29)30(26)36)22-12-6-3-7-13-22/h3,6-10,12-19,33H,2,4-5,11H2,1H3,(H,31,32) |
| InChiKey | HSVRUECLQUGTDS-UHFFFAOYSA-N |
| CID | 134307820 |
| Short Description | MAT2A inhibitor |
