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GSK484 hydrochloride
Axon 3531
- Parent CAS: 1652629-23-6
- Optical Purity: Optically pure
- Soluble in water, DMSO and EtOH
- MF: C27H31N5O3.HCl
- MW: 510.03
Description
GSK484 hydrochloride is a highly potent, selective, and reversible PAD4 inhibitor with an IC50 value of 50 nM (in the absence of calcium).
More Information
| Parent CAS No. | 1652629-23-6 |
|---|---|
| Chemical Name | ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride |
| SMILES | [C@H]1(O)[C@@H](N)CN(C(=O)C2C=C(OC)C3N(C)C(C4N(CC5CC5)C5C=CC=CC=5C=4)=NC=3C=2)CC1.Cl |&1:0,2,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C27H31N5O3.ClH/c1-30-25-20(11-18(13-24(25)35-2)27(34)31-10-9-23(33)19(28)15-31)29-26(30)22-12-17-5-3-4-6-21(17)32(22)14-16-7-8-16;/h3-6,11-13,16,19,23,33H,7-10,14-15,28H2,1-2H3;1H/t19-,23+;/m0./s1 |
| InChiKey | MULKOGJHUZTANI-ADMBKAPUSA-N |
| CID | 86340151 |
| Short Description | PAD4 inhibitor |
GSK484 hydrochloride
PAD4 inhibitor
GSK 484 hydrochloride
GSK-484 hydrochloride
CAS 1652591-81-5
CAS 1652629-23-6
Axon Medchem
Axon 3531
Protein L-arginine
PAD
Inhibitor
Enzymes
Immunology
NETosis
PADI4
Oncology
Neutrophil extracellular traps
Innate immunity
Protein arginine deiminase
Supplier
Vendor
